Vanderbilt Pharmacogenetics

Overview

 

The investigators listed here are all involved in various Vanderbilt Pharmacogenetics Projects.

For their individual bios and information, please click on their respective names.

 

Constantin Aliferis, M.D., Ph.D., joined the faculty in July of 2000 as an Assistant Professor in the Department of Biomedical Informatics and the Vanderbilt-Ingram Cancer Center. He serves as the Director of the Discovery Systems Laboratory.

Dr. Aliferis earned an M.D. from the University of Athens in Athens, Greece. He completed a Fellowship in Medical Informatics at the University of Pittsburgh, and earned his M.S. and Ph.D. degrees from the same university in Intelligent Systems/Medical Informatics.

Dr. Aliferis has published research in Epidemiology, Intelligent Interfaces for data analysis, Bayesian Belief Networks, Temporal Representation and Reasoning, and Machine Learning. In his doctoral dissertation, he pioneered extension of Bayesian Networks to include explicit and hybrid-granularity temporal and causal modelling and dynamic abstraction.

Interests & Current Work:

1. Development and evaluation of machine learning algorithms for:

* large-scale computational causal discovery
* feature selection and construction for classification
* text categorization

2. Medical Decision Support systems for:

* molecular (gene expression and mass spectrometry based) prognostic, diagnostic, and treatment selection models
* normative and evidence-based medicine

3. Temporal Representation and Reasoning in biomedicine

4. Bayesian Networks / Causal Probabilistic Networks

5. Graduate Education

Complete Information

 

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